Related Experiment Video
Updated: May 8, 2026

07:43
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Bilateral transverse sinus stenosis causing intracranial hypertension
M Neil Woodall1, Khoi D Nguyen, Cargill H Alleyne
1Department of Neurological Surgery, Georgia Regents University, Augusta, Georgia, USA.
BMJ Case Reports
|August 22, 2013
Summary
Idiopathic intracranial hypertension (IIH) can be linked to transverse sinus stenosis. In this case, a ventriculoperitoneal shunt effectively resolved IIH symptoms, offering a treatment alternative.
Area of Science:
- Neurology
- Radiology
- Neurosurgery
Background:
- Idiopathic intracranial hypertension (IIH) is a condition often associated with transverse sinus stenosis.
- Transverse sinus stenosis may contribute to increased intracranial pressure and pseudotumor symptoms.
Observation:
- A 19-year-old male presented with IIH and bilateral transverse sinus stenosis.
- CT venography and MRI confirmed the stenosis, revealing dilated collateral veins on VENBOLD sequences.
Findings:
- Treatment options considered included CSF shunting, optic nerve fenestrations, and transverse sinus stenting.
- A ventriculoperitoneal shunt was surgically placed in the patient.
Implications:
- The ventriculoperitoneal shunt led to a prompt resolution of pseudotumor symptoms.
- This case highlights the efficacy of CSF shunting as a treatment for IIH associated with transverse sinus stenosis.
Related Concept Videos
Increased Intracranial Pressure l: Introduction
Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Increased Intracranial Pressure ll: Pathophysiology
Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Cerebral Edema ll: Pathophysiology
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Veins of Head and Neck
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
Mitral Stenosis I: Introduction
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...