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Updated: May 8, 2026

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
Published on: April 17, 2020
[Mediastinitis after esophageal perforation]
J Safránek1, J Geiger, J Klecka
1Chirurgickfá klinika FN Plzen. safranek@fnplzen.cz
Introduction:
Assessment of therapy in patients with mediastinal infection resulting from esophageal perforation.
Material And Methods:
Retrospective (2008-2012) processing of a group of surgically treated patients. The aspects assessed were aetiology, the surgical methods applied and the length of therapy.
Results:
The total number of patients treated was 16. In 8 cases, the aetiology was iatrogenic (3 cases of leaking esophageal anastomosis in consequence of resection of the esophagus, 2 cases of perforation after fundoplication, 1 case of esophageal cardiomyotomy, and 2 cases of perforation during endoscopy). In 4 patients, the aetiology was spontaneous perforation, impacted foreign bodies caused difficulties to 3 patients, and the last cause was acid corrosive esophagitis. A stent was applied in all the patients at the site of the defect. The mediastinitis was drained through the access from thoracotomy or left thoracolaparotomy, respectively (8 cases), or by combination of laparotomy/laparostomy and pleural drainage (5 cases). Pleural (in 3 cases) and neck (1 case) drainage meant minimum intervention. Esophagectomy was not carried out in any of the patients. 4 patients died. The average period of time for which the stent was left in situ was 53.7 days; the average time of hospitalization in surviving patients was 53.4 days.
Conclusion:
Stent application does not show any difference regarding patients' survival (25% mortality), but enables shortening the total therapy time and, predominantly, preserving the native esophagus.
Insights
Esophageal perforation treatment using stents in mediastinitis patients showed a 25% mortality rate. While not impacting survival, stenting shortened therapy duration and preserved the native esophagus.
Area of Science:
- Gastroenterology
- Thoracic Surgery
- Medical Device Technology
Context:
- Mediastinal infection following esophageal perforation presents a significant clinical challenge.
- Surgical management of esophageal perforation requires careful consideration of etiology and intervention strategy.
Purpose:
- To assess the efficacy of esophageal stent placement in managing mediastinal infection secondary to esophageal perforation.
- To evaluate the impact of stenting on treatment duration, complication rates, and esophageal preservation.
Summary:
- A retrospective study analyzed 16 surgically treated patients with esophageal perforation and mediastinitis between 2008-2012.
- Common etiologies included iatrogenic causes (anastomotic leaks, post-fundoplication), spontaneous perforations, foreign bodies, and corrosive esophagitis.
- All patients received esophageal stents, and mediastinal drainage was performed via thoracotomy, thoracolaparotomy, or laparotomy/laparostomy. Esophagectomy was avoided in all cases.
Impact:
- Esophageal stenting did not alter patient survival rates (25% mortality) but significantly reduced overall therapy time.
- The primary benefit of stenting was the successful preservation of the native esophagus, avoiding the need for esophagectomy.
- This approach offers a less invasive strategy for managing complex esophageal perforations.
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