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Updated: May 8, 2026

Erosion Identification in Metacarpophalangeal Joints in Rheumatoid Arthritis using High-Resolution Peripheral Quantitative Computed Tomography
Published on: October 6, 2023
A Renaissance Pope with arthritis following frostbite
1Department of Medicine, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ, USA. bob@pinals.com
Abstract:
Pius II, a 15th century Pope, developed chronic foot pain following frostbite at age 30. Later in life he was progressively disabled by arthritis elsewhere and by colic, which may have been due to kidney stones. The differential diagnosis of his rheumatic disease and its effect on his career are discussed.
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