Related Experiment Video
Updated: Aug 10, 2026

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
Mediterranean spotted fever in children returning from France
T L Treadwell1, S D Phillips, W J Jablonski
1Department of Medicine, Framingham Union Hospital, MA 01701.
Mediterranean spotted fever, a tick-borne illness, is rarely diagnosed in travelers. This report highlights two pediatric cases in southern France, emphasizing travel medicine
Area of Science:
- Pediatrics
- Infectious Diseases
- Travel Medicine
Background:
- Mediterranean spotted fever (MSF) incidence is rising globally.
- MSF is infrequently diagnosed in international travelers.
- Tick-borne diseases pose risks to global travelers.
Observation:
- Two children presented with rash and lymphadenopathy after traveling in southern France.
- Neither child reported a tick bite.
- Clinical presentation mimicked other febrile exanthems.
Findings:
- Both children were diagnosed with MSF via serologic testing.
- Treatment with doxycycline was effective.
- Confirmed MSF in pediatric travelers highlights diagnostic challenges.
Implications:
- International travel can introduce pediatric patients to rare diseases.
- Clinicians should consider MSF in febrile exanthems in travelers.
- Raising awareness of MSF in pediatric travel medicine is crucial.
More Related Videos
08:04Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
Published on: July 9, 2014
07:20Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
Related Concept Videos
Fungal Phylum Microsporidia
Rocky Mountain Spotted Fever
Yellow Fever
Malaria
Toxoplasmosis
American Trypanosomiasis