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Direct diabetes-related costs in young patients with early-onset, long-lasting type 1 diabetes
Christina Bächle1, Andrea Icks, Klaus Straßburger
1Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany. christina.baechle@ddz.uni-duesseldorf.de
Insights
Direct healthcare costs for pediatric type 1 diabetes patients in Germany averaged €3,745 annually. Key expenses included glucose monitoring, insulin pump therapy, and hospitalizations, highlighting areas for cost optimization.
Area of Science:
- Pediatric Endocrinology
- Health Economics
- Diabetes Management
Background:
- Type 1 diabetes (T1D) in children requires lifelong management and incurs significant healthcare costs.
- Early-onset T1D, diagnosed in children aged 0-4 years, presents unique long-term management challenges.
- Understanding direct healthcare costs is crucial for resource allocation and healthcare policy in pediatric T1D.
Purpose of the Study:
- To estimate the direct diabetes-related healthcare costs in pediatric patients with early-onset T1D in Germany.
- To identify the primary cost drivers within this patient cohort.
- To explore demographic and clinical factors associated with variations in healthcare costs.
Main Methods:
- Analysis of a population-based cohort of 1,473 children with T1D onset (0-4 years) from 1993-1999.
- Inclusion of data up to December 31, 2007, with a mean diabetes duration of 10.9 years.
- Utilization of a nationwide prospective documentation system (DPV) to track healthcare services and associated costs from the statutory health insurance perspective.
Main Results:
- Mean annual direct diabetes-related healthcare costs were €3,745 per patient-year.
- Major cost categories included glucose self-monitoring (28.5%), continuous subcutaneous insulin infusion (25.0%), hospitalizations (22.1%), and insulin (18.4%).
- Higher costs were associated with female gender, pubertal age, and poor glycemic control; lower costs were linked to a migration background.
Conclusions:
- Glucose self-monitoring, insulin pump therapy, hospitalizations, and insulin represent the primary direct costs in long-duration pediatric T1D.
- Optimizing glycemic control, especially during puberty, through intensified care, education, and tailored regimens can reduce direct costs.
- These findings emphasize the economic impact of pediatric T1D and the potential for cost savings through improved management strategies.
Objective:
To estimate diabetes-related direct health care costs in pediatric patients with early-onset type 1 diabetes of long duration in Germany.
Research Design And Methods:
Data of a population-based cohort of 1,473 subjects with type 1 diabetes onset at 0-4 years of age within the years 1993-1999 were included (mean age 13.9 (SD 2.2) years, mean diabetes duration 10.9 (SD 1.9) years, as of 31.12.2007). Diabetes-related health care services utilized in 2007 were derived from a nationwide prospective documentation system (DPV). Health care utilization was valued in monetary terms based on inpatient and outpatient medical fees and retail prices (perspective of statutory health insurance). Multiple regression models were applied to assess associations between direct diabetes-related health care costs per patient-year and demographic and clinical predictors.
Results:
Mean direct diabetes-related health care costs per patient-year were €3,745 (inter-quartile range: 1,943-4,881). Costs for glucose self-monitoring were the main cost category (28.5%), followed by costs for continuous subcutaneous insulin infusion (25.0%), diabetes-related hospitalizations (22.1%) and insulin (18.4%). Female gender, pubertal age and poor glycemic control were associated with higher and migration background with lower total costs.
Conclusions:
Main cost categories in patients with on average 11 years of diabetes duration were costs for glucose self-monitoring, insulin pump therapy, hospitalization and insulin. Optimization of glycemic control in particular in pubertal age through intensified care with improved diabetes education and tailored insulin regimen, can contribute to the reduction of direct diabetes-related costs in this patient group.
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