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Related Concept Videos

Multiple Allele Traits01:49

Multiple Allele Traits

The Concept of Multiple Allelism
Polygenic Traits01:18

Polygenic Traits

When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
Polygenic Traits01:18

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When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
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Heritability

Heritability is a statistical concept that measures the degree to which genetic differences among individuals contribute to trait variations within a population. It is a fundamental idea in genetics, often prone to misinterpretation. Heritability is expressed as a percentage, reflecting the proportion of variation in a specific trait across a population that can be linked to genetic differences. However, it's important to understand that heritability does not determine how "genetic" a trait is,...
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Gene-Environment Interactions

Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...

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Related Experiment Video

Updated: May 8, 2026

Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization
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Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization

Published on: July 27, 2021

Selection on QTL and complex traits in complex environments.

Thomas Mitchell-Olds

    Molecular Ecology
    |August 23, 2013
    PubMed
    Summary
    This summary is machine-generated.

    Genetic variation for complex traits in diverse environments was studied in Arabidopsis thaliana. Findings suggest that genetic trade-offs in flowering time contribute to maintaining genetic diversity across populations.

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    Published on: July 27, 2021

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    Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

    Published on: June 21, 2018

    Area of Science:

    • Evolutionary biology
    • Plant genetics
    • Ecology

    Background:

    • Understanding genetic variation for complex traits in heterogeneous environments is crucial in biology.
    • Arabidopsis thaliana is a model organism for studying plant adaptation and evolution.

    Purpose of the Study:

    • To analyze quantitative trait loci (QTL) influencing ecologically important phenotypes in Arabidopsis thaliana.
    • To quantify the selective consequences of life history, morphological traits, and QTL on fitness components.
    • To investigate genetic trade-offs and their role in maintaining genetic variation across different environments.

    Main Methods:

    • Mapping populations of Arabidopsis thaliana were grown in four distinct European habitats.
    • Causal modeling was employed to assess the effects of traits and QTL on fitness.
    • Phenotypic and fitness data were compared across environments to identify genetic trade-offs.

    Main Results:

    • Phenology QTL were found to colocalize with known flowering time genes and novel loci.
    • Most QTL influenced fitness indirectly through life history and size traits.
    • No evidence for genetic trade-offs in phenology or growth traits was observed.
    • Genetic trade-offs for fitness emerged due to opposing fitness effects of flowering time in different environments.

    Conclusions:

    • Changes in QTL effects and selective consequences across environments may play a role in maintaining genetic variation among populations.
    • Flowering time's variable fitness effects contribute to genetic trade-offs and population-level genetic diversity.