Related Experiment Video
Updated: Aug 21, 2026
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Treatment of actinic prurigo with intermittent short-course topical 0.05% clobetasol 17-propionate. A preliminary
P R Lane1, A A Moreland, D J Hogan
1Department of Medicine, University Hospital, University of Saskatchewan, Saskatoon, Canada.
Abstract:
Actinic prurigo is a chronic familial photodermatosis that occurs mostly in Amerindians. Eight patients with actinic prurigo were given intermittent 3- to 14-day courses of topical 0.05% clobetasol 17-propionate cream or ointment in 1988 and 1989. Seven out of eight patients cleared or markedly improved. All of the patients had been resistant previously to milder topical corticosteroids. There have been no side effects. This therapy offers an effective alternative to systemic corticosteroids, oral psoralen with long-wave UV radiation in the A range, or thalidomide.
