Related Experiment Video
Updated: May 8, 2026

Kinetic Measurement and Real Time Visualization of Somatic Reprogramming
Published on: July 30, 2016
Secondary cell reprogramming systems: as years go by
1Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario M5T 3H7, Canada; Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Ontario, Canada.
Abstract:
The groundbreaking discovery of the induced pluripotent stem cells in 2006 brought a major paradigm shift in our understanding of the plasticity of differentiated cells. An unprecedented effort has been invested to elucidate the underpinning molecular mechanisms of the dramatic changes in cell properties, using the powerful secondary reprogramming systems (2°RS). This review outlines the key components of the 2°RS, its recent development and applications that have led to a deeper understanding of the 'magic' of induced cell fate changes.
More Related Videos
10:52Isolation of Adult Human Dermal Fibroblasts from Abdominal Skin and Generation of Induced Pluripotent Stem Cells Using a Non-Integrating Method
Published on: January 19, 2020
11:00Reprogramming Mouse Embryonic Fibroblasts with Transcription Factors to Induce a Hemogenic Program
Published on: December 16, 2016
Related Concept Videos
Somatic to iPS Cell Reprogramming
Methods of Nuclear Reprogramming
Introduction to Nuclear Reprogramming
Induced Pluripotent Stem Cells
Induced Pluripotent Stem Cells
Somatic cells are...
Induced Pluripotent Stem Cells