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[Obesity and radiation: technical difficulties, toxicity and efficacy]
Summary
Obesity rates have risen in France, increasing cancer incidence. Obesity complicates radiotherapy by affecting treatment delivery, toxicity, and patient outcomes.
Area of Science:
- Oncology
- Radiotherapy
- Public Health
Context:
- Rising obesity rates in France over the past two decades.
- Obesity's significant impact on cancer incidence.
- Challenges in cancer treatment due to patient weight.
Purpose:
- To examine the multifaceted impact of obesity on cancer radiotherapy.
- To highlight the physical, technical, and dosimetric challenges.
- To assess effects on patient toxicity, local control, and survival.
Summary:
- Obesity presents physical, technical, and dosimetric challenges in radiotherapy.
- Increased acute and late toxicity are observed in obese cancer patients.
- Obesity negatively affects local tumor control and overall patient survival.
Impact:
- Understanding these impacts is crucial for optimizing radiotherapy for obese patients.
- Informing clinical practice to mitigate obesity-related radiotherapy complications.
- Addressing obesity as a critical factor in cancer treatment and survivorship.
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