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Updated: May 8, 2026

Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
Published on: August 18, 2016
Global coronary arteries spasm in a young patient
Homa Falsoleiman1, Baktash Bayani, Mashalla Dehghani
1Associate Professor, Mashhad Cardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Background:
Coronary artery spasm is a transient narrowing of coronary arteries that slows or stops blood flow through the artery.
Case Report:
We present a 42-year-smoker man without any medical problem who developed syncope. Coronary angiography revealed diffuse significant narrowing of proximal left anterior descending artery (LAD), 90% osteal stenosis of large obtuse marginal (OM), 90% diffuse narrowing of proximal right coronary artery (RCA), which was relieved by intracoronary administration of nitrate. He was discharged on calcium channel blockers and nitrates but one month later developed syncope again and died.
Conclusion:
Multivessel coronary artery spasm should be considered in young smoker patients without any other coronary risk factors who present with syncope.
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