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Reply: To PMID 23490292

Joseph Louis Bobadilla, Martha Wynn, Girma Tefera

    Journal of Vascular Surgery
    |August 27, 2013
    PubMed
    Summary

    No abstract available in PubMed .

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    Drug Metabolism: Phase II Reactions01:14

    Drug Metabolism: Phase II Reactions

    Phase II reactions are essential for the detoxification and elimination of drugs from the body. These reactions involve the conjugation of parent drugs or their phase I metabolites with endogenous molecules, resulting in more hydrophilic drug conjugates. The primary conjugation reactions in this phase are sulfation and glucuronidation. Both sulfation and glucuronidation typically produce biologically inactive metabolites. However, in some cases involving prodrugs, active metabolites may be...

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