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Generating CD8 T cell heterogeneity: attack of the clones

Heather D Marshall1, Susan M Kaech

  • 1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

Immunity
|August 27, 2013
PubMed

Pathogen-induced inflammation modulates CD8 T cell effector and memory differentiation. In this issue of Immunity, Plumlee et al. (2013) demonstrate that clonally distinct CD8 T cells have the ability to generate numerous types of effector cell fates based on extrinsic pathogen-induced environmental cues.

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