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Updated: Aug 18, 2026

Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface
Published on: February 21, 2011
[Acute effects of smoking a single cigarette on airway dynamics]
1China-Japan Friendship Hospital.
Abstract:
The maximal expiratory flow-volume curve (MEFV) and airway resistance (Raw) were studied before and after smoking a single cigarette in 51 male and 51 female healthy nonsmokers. The results showed that there was a significant increase in Raw after smoking, but no change in MEFV. The acute airway response after smoking a single cigarette represents vagally mediated protective reflex. Raw is the most sensitive test in detecting acute airway constriction. There is no sexual difference in acute effects of smoking.
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