Related Experiment Video
Updated: Aug 20, 2026

Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples
Published on: May 4, 2012
[Antibodies against alpha, beta, and gamma crystallins in human serum]
1Eye Research Institute, Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou, Guangdong Province.
Abstract:
Serum antibodies against alpha, beta, and gamma crystallins in 79 normal subjects and 38 patients with senile cataract were determined by ELISA, with the result that the presence of the antibodies was related to age, not to sex, and the rate of presence in patients with senile cataract did not differ from that of controls. The relationship between the presence of the antibodies and senile cataract was discussed.
Related Concept Videos
Antibody Structure
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Cross-reactivity
Antibody Structure and Classes
The basic structure of an antibody consists of four protein chains: two identical heavy chains and two identical light chains. These chains are held together by disulfide bonds and other non-covalent interactions, forming a Y-shaped structure.

