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Anterior chamber depth during hemodialysis

Carolina Pelegrini Barbosa Gracitelli1, Francisco Rosa Stefanini, Fernando Penha

  • 1Ophthalmology Department, University of São Paulo - UNIFESP, São Paulo, Brazil.

Clinical Ophthalmology (Auckland, N.Z.)
|August 27, 2013
PubMed

Insights

Hemodialysis (HD) can cause changes in eye anatomy. This study found that while axial length remained stable, anterior chamber depth significantly decreased during HD sessions in patients.

Area of Science:

  • Ophthalmology
  • Nephrology
  • Medical Physiology

Background:

  • Glaucoma exacerbations can occur during hemodialysis due to anterior chamber depth alterations.
  • Understanding these ocular changes is crucial for managing patients undergoing hemodialysis.

Purpose of the Study:

  • To investigate changes in anterior chamber depth and axial length during hemodialysis sessions.
  • To assess the ocular hemodynamic effects of hemodialysis therapy.

Main Methods:

  • Prospective study involving 35 patients (67 eyes).
  • Ultrasonic biometry used to measure axial length and anterior chamber depth at three time points during hemodialysis.
  • Body weight and blood pressure were recorded pre- and post-hemodialysis.

Main Results:

  • No significant difference was observed in axial length measurements throughout the hemodialysis sessions (P = 0.241).
  • A statistically significant decrease in anterior chamber depth was noted during hemodialysis (P = 0.002).

Conclusions:

  • Hemodialysis sessions are associated with significant changes in anterior chamber depth.
  • These findings support the clinical observation of altered anterior chamber depth in patients undergoing hemodialysis.
Abstract

Keywords:
acute angle-closure glaucomaanterior chamberaxial lengthhemodialysis

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