Related Experiment Video
Updated: May 8, 2026

Laser Doppler: A Tool for Measuring Pancreatic Islet Microvascular Vasomotion In Vivo
Published on: March 8, 2018
Diabetic neuropathy. Correlation with other diabetic microvascular complications
Sami A Bashi1, Salem D Alsuwaidan, Adnan A Awada
1Department of Medicine, King Fahad National Guard Hospital, PO Box 22490, Riyadh 11426, Kingdom of Saudi Arabia. Tel. +966 (1) 2520088 Ext. 5446. Fax. + 966 (1) 2520140.
Objective:
We studied the frequency of neuropathy in Saudi patients with definite diabetic microvascular complications and compared it to patients without complications. A high frequency of neuropathy in patients with definite microvascular complications would suggest a vascular etiology.
Methods:
The study group consisted of 201 type-2 diabetic patients followed in the diabetic clinic of King Fahad National Guard Hospital, Riyadh, Kingdom of Saudi Arabia. These patients were screened for microvascular disease. Only symmetrical distal sensory and motor neuropathy cases were included in the study. Screening for retinopathy was carried out according to Klien`s criteria and nephropathy was diagnosed if albuminuria, microalbuminuria, abnormal blood urea nitrogen or creatinine was present.
Results:
There was a strong correlation between the prevalence of diabetic peripheral neuropathy, retinopathy (P<0.001) and nephropathy (P<0.01), in patients with type 2 diabetes mellitus. This strong correlation suggests a common underlying pathogenesis.
Conclusion:
We conclude that microangiopathy may be a major factor in the pathogenesis of diabetic neuropathy. Major risk factors for microangiopathy are the degree of glycemic control and duration of diabetes.
More Related Videos
Related Concept Videos
Diabetic Retinopathy
Diabetic Neuropathy
Complications of Diabetes Mellitus
Diabetic Foot Ulcer
Diabetic Nephropathy
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...

