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Updated: May 8, 2026
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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
Association between renal function, diastolic dysfunction, and postoperative atrial fibrillation following cardiac
Su-Kiat Chua1, Kou-Gi Shyu, Ming-Jen Lu
1Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University.
Summary
Reduced kidney function in cardiac surgery patients is linked to increased left ventricular diastolic dysfunction and a higher risk of postoperative atrial fibrillation (POAF). This highlights renal function as a key predictor of POAF.
Area of Science:
- Cardiology
- Nephrology
- Cardiac Surgery
Background:
- Renal dysfunction is a known risk factor for atrial fibrillation.
- The relationship between renal function, left ventricular (LV) diastolic dysfunction, and postoperative atrial fibrillation (POAF) requires further investigation.
Purpose of the Study:
- To investigate the associations between estimated glomerular filtration rate (eGFR), LV diastolic dysfunction, and POAF in patients undergoing cardiac surgery.
Main Methods:
- Prospective enrollment of 265 cardiac surgery patients.
- Echocardiography performed pre-operatively to assess LV diastolic dysfunction (E/e' ratio).
- Patients categorized into three groups based on eGFR levels (≥90, 60-90, <60 ml·min(-1)·1.73m(-2)).
Main Results:
- POAF incidence increased significantly with declining eGFR: 15.2% (eGFR ≥90), 27.8% (eGFR 60-90), and 49.4% (eGFR <60).
- LV diastolic dysfunction (E/e' >15) prevalence also rose with decreased renal function (19.0% to 48.3%).
- Lower eGFR independently predicted POAF (OR 1.90; P=0.002), and eGFR correlated inversely with E/e' ratio (r=-0.39, P<0.001).
Conclusions:
- Decreased eGFR is significantly associated with increased LV diastolic dysfunction in cardiac surgery patients.
- Impaired renal function is an independent predictor of POAF.
- These findings underscore the importance of renal function assessment in predicting POAF risk.
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