Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Toxins01:36

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Toxic Reactions: Overview01:26

Toxic Reactions: Overview

When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
The Periodic Table and Organismal Elements01:27

The Periodic Table and Organismal Elements

Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally occurring, and only a few of them are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.
Periodic Table Provides Information...
Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Allergic Reactions02:06

Allergic Reactions

Overview

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aluminium adjuvants and childhood health: a call for science.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)·2025
Same author

Dietary Egg White Hydrolysate Prevents Male Reproductive Dysfunction after Long-Term Exposure to Aluminum in Rats.

Metabolites·2022
Same author

The influence of aluminium and copper upon the early aggregatory behaviour and size of Islet amyloid polypeptide under simulated physiological conditions.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)·2022
Same author

The size of micro-crystalline tyrosine (MCT®) influences its recognition and uptake by THP-1 macrophages <i>in vitro</i>.

RSC advances·2022
Same author

Aluminium co-localises with Biondi ring tangles in Parkinson's disease and epilepsy.

Scientific reports·2022
Same author

Aluminum and Tau in Neurofibrillary Tangles in Familial Alzheimer's Disease.

Journal of Alzheimer's disease reports·2021
Same journal

Deciphering the impact of wastewater treatment plants from other inputs on quaternary ammonium compounds (QACs) in surface waters and sediments.

Environmental science. Processes & impacts·2026
Same journal

Microfluidics isolate the rapid electrostatic regime of Pb(II) adsorption onto carboxylated nanoparticles.

Environmental science. Processes & impacts·2026
Same journal

Soil organic matter composition controls neonicotinoid transport and accumulation to benthic macroinvertebrate communities in agricultural drains.

Environmental science. Processes & impacts·2026
Same journal

Freeze-thaw impacts on physicochemical properties and mineral-organic components of various loess soils.

Environmental science. Processes & impacts·2026
Same journal

Occurrence, spatial variation, and exposure risk of 14 bisphenol analogues in drinking water in Sichuan, China.

Environmental science. Processes & impacts·2026
Same journal

Sublethal toxicity assessments of 7PPD-quinone and 77PD-quinone in zebrafish embryos and sac-fry.

Environmental science. Processes & impacts·2026
See all related articles

Related Experiment Video

Updated: May 8, 2026

Removal of Trace Elements by Cupric Oxide Nanoparticles from Uranium In Situ Recovery Bleed Water and Its Effect on Cell Viability
09:23

Removal of Trace Elements by Cupric Oxide Nanoparticles from Uranium In Situ Recovery Bleed Water and Its Effect on Cell Viability

Published on: June 21, 2015

Human exposure to aluminium.

Christopher Exley1

  • 1The Birchall Centre, Lennard-Jones Laboratories, Keele University, Staffordshire, UK. c.exley@keele.ac.uk.

Environmental Science. Processes & Impacts
|August 29, 2013
PubMed
Summary
This summary is machine-generated.

Human activities are increasing aluminium in the environment and our bodies. Understanding human exposure to aluminium and its health effects is crucial for safe living in this "aluminium age".

More Related Videos

An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing
09:29

An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing

Published on: May 13, 2020

Facile Preparation of Ultrafine Aluminum Hydroxide Particles with or without Mesoporous MCM-41 in Ambient Environments
05:50

Facile Preparation of Ultrafine Aluminum Hydroxide Particles with or without Mesoporous MCM-41 in Ambient Environments

Published on: May 11, 2017

Related Experiment Videos

Last Updated: May 8, 2026

Removal of Trace Elements by Cupric Oxide Nanoparticles from Uranium In Situ Recovery Bleed Water and Its Effect on Cell Viability
09:23

Removal of Trace Elements by Cupric Oxide Nanoparticles from Uranium In Situ Recovery Bleed Water and Its Effect on Cell Viability

Published on: June 21, 2015

An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing
09:29

An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing

Published on: May 13, 2020

Facile Preparation of Ultrafine Aluminum Hydroxide Particles with or without Mesoporous MCM-41 in Ambient Environments
05:50

Facile Preparation of Ultrafine Aluminum Hydroxide Particles with or without Mesoporous MCM-41 in Ambient Environments

Published on: May 11, 2017

Area of Science:

  • Environmental Science
  • Human Health
  • Geochemistry

Background:

  • Human activities have disrupted natural aluminium geochemical cycles.
  • This disruption has led to increased aluminium entry into the biotic cycle.
  • Aluminium accumulation in biota, particularly humans, is a growing concern.

Purpose of the Study:

  • To investigate the extent of human exposure to aluminium.
  • To understand the consequences of increased aluminium body burden.
  • To provide insights for safe and effective coexistence with aluminium.

Main Methods:

  • Analysis of human activities impacting aluminium biogeochemical cycling.
  • Assessment of aluminium entry pathways into the biotic system.
  • Review of current and projected human exposure levels and body burdens.

Main Results:

  • Human activities have significantly altered aluminium's environmental fate.
  • A continuous increase in aluminium exposure and accumulation is observed.
  • The 'aluminium age' signifies a critical juncture for human health.

Conclusions:

  • Urgent need to comprehend human aluminium exposure routes and impacts.
  • Developing strategies for safe human interaction with elevated environmental aluminium is imperative.
  • Further research is required to mitigate risks associated with the 'aluminium age'.