Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Vaccinations

Vaccinations

Microorganisms in Medicine and Therapeutics

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.

Cancer Vaccines

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

Vaccines

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...

Vaccine Production

Vaccine Production

Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...

Clinical Significance of Antibiotic Resistance

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hydropower generation by transpiration from microporous alumina.

Scientific reports·2021

Same author

The Inescapable Conundrum of Klippel-Feil Syndrome Airway: Case Reports.

AANA journal·2021

Same author

Diamidoximated cellulosic bioadsorbents from hemp stalks for elimination of uranium (VI) and textile waste in aqueous systems.

Journal of hazardous materials·2021

Same author

Commentary: Deep anterior lamellar keratoplasty: The challenges and solutions.

Indian journal of ophthalmology·2021

Same author

Commentary: Potential transmissibility of SARS-CoV-2 infection via donor corneal tissue.

Indian journal of ophthalmology·2021

Same author

Indian contribution toward biomedical research and development in COVID-19: A systematic review.

Indian journal of pharmacology·2021

Search research articles

Related Experiment Video

Updated: May 8, 2026

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens

Published on: May 19, 2020

Anthrax vaccines: present status and future prospects.

Manpreet Kaur¹, Samer Singh, Rakesh Bhatnagar

¹Laboratory of Molecular Biology and Genetic Engineering, School of Biotechnology, Jawaharlal Nehru University, New Delhi 110067, Delhi, India.

Expert Review of Vaccines

|August 30, 2013

Summary

Anthrax management is critical due to Bacillus anthracis bioterrorism threats. Research focuses on understanding anthrax pathogenesis and developing advanced vaccines and treatments for fulminant stages.

More Related Videos

Expression of Exogenous Antigens in the Mycobacterium bovis BCG Vaccine via Non-genetic Surface Decoration with the Avidin-biotin System

Expression of Exogenous Antigens in the Mycobacterium bovis BCG Vaccine via Non-genetic Surface Decoration with the Avidin-biotin System

Published on: January 31, 2018

Enrichment of Native and Recombinant Extracellular Vesicles of Mycobacteria

Enrichment of Native and Recombinant Extracellular Vesicles of Mycobacteria

Published on: December 8, 2023

Related Experiment Videos

Last Updated: May 8, 2026

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens

Published on: May 19, 2020

Expression of Exogenous Antigens in the Mycobacterium bovis BCG Vaccine via Non-genetic Surface Decoration with the Avidin-biotin System

Expression of Exogenous Antigens in the Mycobacterium bovis BCG Vaccine via Non-genetic Surface Decoration with the Avidin-biotin System

Published on: January 31, 2018

Enrichment of Native and Recombinant Extracellular Vesicles of Mycobacteria

Enrichment of Native and Recombinant Extracellular Vesicles of Mycobacteria

Published on: December 8, 2023

Area of Science:

Microbiology
Infectious Diseases
Biodefense

Background:

Bacillus anthracis poses a significant biowarfare and bioterrorism threat, highlighted by the 2001 US mail attacks.
The deliberate dissemination of anthrax spores necessitates enhanced understanding of its pathogenesis and improved medical countermeasures.
Current research prioritizes developing effective vaccines and therapeutics for advanced anthrax infection stages.

Purpose of the Study:

To provide an overview of anthrax pathogenesis.
To summarize recent advancements in anthrax management strategies post-2001.
To outline future research perspectives in combating anthrax.

Main Methods:

Review of current scientific literature on anthrax pathogenesis.
Analysis of post-2001 research on anthrax vaccines and therapeutics.
Synthesis of information on medical intervention strategies for anthrax.

Main Results:

Significant progress has been made in understanding anthrax pathogenesis and developing medical interventions.
New vaccine candidates and therapeutic approaches are emerging.
Focus remains on controlling the fulminant stage of anthrax when toxemia is present.

Conclusions:

Continued research is vital for effective anthrax management against natural and deliberate exposures.
Development of safe, efficacious vaccines and advanced treatments is crucial.
A comprehensive approach is needed to address the threat of Bacillus anthracis.