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Hepatitis

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Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...

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Cirrhosis I: Introduction

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Related Experiment Video

Updated: May 8, 2026

A Hepatocellular Cancer Patient-Derived Organoid Xenograft Model to Investigate Impact of Liver Regeneration on Tumor Growth

A Hepatocellular Cancer Patient-Derived Organoid Xenograft Model to Investigate Impact of Liver Regeneration on Tumor Growth

Published on: February 2, 2024

[Recurrent hepatocellular carcinoma].

Yoichi Ishizaki¹, Seiji Kawasaki

¹Dept. of Hepatobiliary-Pancreatic Surgery, Juntendo University School of Medicine, Japan.

Gan to Kagaku Ryoho. Cancer & Chemotherapy

|August 30, 2013

Summary

This summary is machine-generated.

Recurrent hepatocellular carcinoma (HCC) has a poor prognosis. Effective treatment for recurrent HCC, like repeat hepatectomy for select patients, is crucial for improving outcomes.

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An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

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Published on: September 12, 2019

Area of Science:

Hepatobiliary oncology
Surgical oncology
Gastroenterology

Context:

Hepatocellular carcinoma (HCC) recurrence after curative treatment is common.
Prognosis for recurrent HCC significantly impacts long-term patient survival.
Current treatment strategies for recurrent HCC require optimization.

Purpose:

To outline optimal treatment strategies for recurrent hepatocellular carcinoma (HCC).
To emphasize the importance of consistent treatment criteria for primary and recurrent HCC.
To identify patient subgroups suitable for repeat hepatectomy.

Summary:

Long-term outcomes for hepatocellular carcinoma (HCC) patients are limited by high recurrence rates.
Treatment for recurrent HCC should follow the same principles as for primary HCC.
Repeat hepatectomy is recommended for patients with fewer than 3 recurrent tumors and good liver function (Child-Pugh A or non-cirrhotic).

Impact:

Improved clinical decision-making for managing recurrent HCC.
Enhanced survival rates for patients undergoing treatment for recurrent disease.
Standardized approach to recurrent HCC management, optimizing surgical interventions.