Related Experiment Video

Updated: May 8, 2026

Isolation of Retinal Pigment Epithelial Cells from Guinea Pig Eyes
05:06

Isolation of Retinal Pigment Epithelial Cells from Guinea Pig Eyes

Published on: May 9, 2023

[Childhood retinal detachment: ROP and myopia]

B Müller1, A M Joussen

  • 1Augenklinik der Charité Universitätsmedizin Berlin (Standorte Virchow Klinikum und Klinikum Benjamin Franklin).

Klinische Monatsblatter Fur Augenheilkunde
|August 30, 2013
PubMed

Insights

Retinopathy of prematurity (ROP) can lead to tractional retinal detachment, with outcomes depending on early treatment. Lifelong monitoring is crucial for ROP residuals due to risks of further retinal detachment.

Area of Science:

  • Ophthalmology
  • Neonatal Medicine
  • Retinal Vascular Diseases

Context:

  • Retinopathy of prematurity (ROP) arises from incomplete retinal vascularization after premature birth.
  • ROP progresses through phases involving hypoxia, vascular proliferation, and vitreoretinal traction.
  • ROP residuals can manifest as tractional or rhegmatogenous retinal detachments later in life.

Purpose:

  • To review the causes and treatment strategies for retinopathy of prematurity-related tractional retinal detachment.
  • To discuss detachments in ROP residuals during childhood and early adulthood.
  • To highlight the long-term implications and monitoring needs for ROP patients.

Summary:

  • Phase I of ROP involves delayed vascular growth and hypoxia; Phase II features hypoxia-driven vascular proliferation causing traction.
  • Treatment outcomes for tractional detachment in ROP vary, with re-attachment rates over 70% reported for ROP IV a, but limited functional and anatomic results in later stages.
  • Myopia is associated with ROP, increasing the risk of rhegmatogenous detachment in ROP residuals, necessitating lifelong ophthalmological surveillance.

Impact:

  • Understanding ROP progression and treatment effects is vital for managing long-term visual outcomes.
  • Early and appropriate interventions can influence the success of treating ROP-related retinal detachments.
  • Lifelong monitoring is essential for individuals with a history of ROP to detect and manage potential complications like rhegmatogenous detachment.

More Related Videos

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate05:58

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Published on: September 11, 2013

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model05:56

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...