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Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
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Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF

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[Management of systemic lupus erythematosus-Including secondary antiphospholipid syndrome, fertility and pregnancy : S3 guidelines of the German Society for Rheumatology and Clinical Immunology and the German Society for Neurology (DGN), German Society for Internal Medicine (DGIM), German Cardiac Society (DGK), Society for Thrombosis and Hemostasis Research (GTH), German Society for Hematology and Medical Oncology (DGHO), German Society for Pediatric and Adolescent Medicine (DGKJ), Society for Pediatric and Adolescent Rheumatology (GKJR), German Society for Nephrology (DGfN), German Society for Pneumology and Ventilation Medicine (DGP), German Rheumatism League National Association, Lupus Erythematosus Self-help Community, German Dermatological Society (DDG). Version: 1.2].

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Related Experiment Video

Updated: May 8, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
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[Pregnancy and inflammatory rheumatic diseases].

R Fischer-Betz1, S Späthling-Mestekemper

  • 1Poliklinik für Rheumatologie, Heinrich Heine Universität Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland, rebecca.fischer@med.uni-duesseldorf.de.

Zeitschrift Fur Rheumatologie
|August 31, 2013
PubMed
Summary

Women with rheumatic diseases can achieve successful pregnancies with proper preconception care and medication management. Optimal shared decision-making is crucial for managing risks and ensuring healthy outcomes for both mother and baby.

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An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
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Last Updated: May 8, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
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Area of Science:

  • Rheumatology
  • Obstetrics
  • Maternal-Fetal Medicine

Context:

  • Pregnancy in women with rheumatic diseases presents unique challenges.
  • Requires careful management and shared decision-making between patients and physicians.
  • Successful pregnancy outcomes are achievable for the majority.

Purpose:

  • To highlight the importance of preconception care for women with rheumatic diseases.
  • To emphasize risk assessment and appropriate medication use during pregnancy.
  • To guide optimal management strategies for successful pregnancy.

Summary:

  • Optimal preconception care is essential for women with rheumatic diseases.
  • Careful risk assessment and judicious use of antirheumatic drugs are key.
  • The majority of women with rheumatic diseases can have healthy pregnancies and babies.

Impact:

  • Improves pregnancy outcomes for women with rheumatic diseases.
  • Provides a framework for shared decision-making in managing rheumatic conditions during pregnancy.
  • Contributes to the well-being of mothers and newborns affected by rheumatic diseases.