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Coronary artery disease in Bangladesh: a review

A K M Monwarul Islam1, A A S Majumder

  • 1Registrar, Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka 1207, Bangladesh.

Indian Heart Journal
|September 3, 2013
PubMed

Insights

Coronary artery disease (CAD) is a major health issue in Bangladesh, disproportionately affecting South Asians. Further research is crucial to understand its unique risk factors and progression in the region.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Coronary artery disease (CAD) is the leading cause of mortality in Bangladesh.
  • Bangladeshis, like other South Asians, are predisposed to premature, aggressive, and severe CAD.
  • The pathophysiology of CAD in this population remains poorly understood.

Purpose of the Study:

  • To highlight the significant public health challenge posed by CAD in Bangladesh.
  • To identify known and potential risk factors contributing to CAD in the Bangladeshi population.
  • To emphasize the need for comprehensive research into CAD in Bangladesh.

Main Methods:

  • Review of existing knowledge on CAD prevalence and risk factors in Bangladesh and South Asia.
  • Identification of conventional, lifestyle-related, and novel risk factors.
  • Assessment of the current research gap regarding CAD in Bangladesh.

Main Results:

  • CAD is prevalent and severe in Bangladesh, with early onset.
  • Key contributing factors include genetic predisposition, metabolic syndrome, conventional risk factors, lifestyle choices (diet, physical activity), and novel factors like hypovitaminosis D, arsenic contamination, and air pollution.
  • Current understanding of CAD's specific mechanisms in Bangladesh is limited.

Conclusions:

  • Urgent need for large-scale epidemiological, genetic, and clinical research on CAD in Bangladesh.
  • Understanding unique regional factors is critical for effective prevention and management strategies.
  • Addressing CAD requires a multi-faceted approach considering genetic, lifestyle, and environmental influences.

Keywords:
Air pollutionArsenicBangladeshCoronary artery diseaseVitamin D deficiency

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