Related Experiment Video
Updated: May 8, 2026

A Minimally Invasive Model to Analyze Endochondral Fracture Healing in Mice Under Standardized Biomechanical Conditions
Published on: March 22, 2018
Intraprosthetic screw fixation increases primary fixation stability in periprosthetic fractures of the femur - a
Stephan Brand1, Johannes Klotz2, Thomas Hassel2
1Trauma Department Hannover Medical School, MHH, Germany.
Background:
The purpose of this study was to develop a new fixation technique for the treatment of periprosthetic fractures using intraprosthetic screw fixation. The goal was to biomechanically evaluate the increase in primary fixation stability compared to unicortical locked-screw plating.
Methods:
A Vancouver C periprosthetic fracture was simulated in femur prosthesis constructs. Fixation was then performed with either unicortical locked-screw plating using the LISS-plate or with intraprosthetic screw fixation. Fixation stability was compared in an axial load-to-failure model.
Results:
The intraprosthetic fixation model was superior to the unicortical locked-screw fixation in all tested devices. The intraprosthetic fixation model required 11,807N±1596N for failure and the unicortical locked-screw plating required 7649N±653N (p=0.002).
Conclusion:
Intraprosthetic screw anchorage with a special prosthesis drill enhances the primary stability in treating periprosthetic fractures by internal fixation.
More Related Videos
05:34A Mini-Invasive Internal Fixation Technique for Studying Immobilization-Induced Knee Flexion Contracture in Rats
Published on: May 20, 2019
09:07An Anesthesia, Surgery, and Harvest Method for the Evaluation of Transpedicular Screws Using an In Vivo Porcine Lumbar Spine Model
Published on: May 31, 2017