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Updated: May 8, 2026

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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Using a cognitive plasticity measure to detect mild cognitive impairment
Alicia Sales-Galán1, Juan Carlos Meléndez-Moral, Teresa Mayordomo-Rodríguez
1Department of Developmental Psychology, Faculty of Psychology, University of Valencia, Spain.
Summary
Older adults with mild cognitive impairment (MCI) show learning capacity and cognitive plasticity, with improvements maintained after a delay. The Spain-Complutense Verbal Learning Test (TAVEC) effectively measures this plasticity and indicates impairment.
Area of Science:
- Neuroscience
- Gerontology
- Cognitive Psychology
Background:
- Cognitive plasticity is crucial for maintaining function in aging populations.
- Mild cognitive impairment (MCI) may affect learning and memory retention.
- Understanding plasticity in MCI is vital for early intervention strategies.
Purpose of the Study:
- To compare cognitive plasticity between healthy older adults and those with MCI.
- To determine if participants with MCI exhibit learning and memory consolidation.
- To assess the Spain-Complutense Verbal Learning Test (TAVEC) as a measure of cognitive plasticity and impairment.
Main Methods:
- A total of 113 participants aged over 65 were recruited.
- Participants were divided into two groups: healthy controls (N=62) and mild cognitive impairment (MCI) (N=51).
- Cognitive plasticity was assessed using the Spain-Complutense Verbal Learning Test (TAVEC).
Main Results:
- Healthy participants demonstrated superior performance compared to the MCI group.
- Participants with MCI showed significant learning capacity and cognitive plasticity.
- Improvements in learning and plasticity were sustained in the MCI group after a delay.
Conclusions:
- The Spain-Complutense Verbal Learning Test (TAVEC) is a suitable tool for measuring cognitive plasticity in older adults.
- Cognitive plasticity is present in individuals with mild cognitive impairment.
- TAVEC can serve as an effective indicator of cognitive impairment in older populations.

