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Updated: May 8, 2026

The Use of Chemostats in Microbial Systems Biology
Published on: October 14, 2013
In scarcity and abundance: metabolic signals regulating cell growth
Shady Saad1, Matthias Peter, Reinhard Dechant
1Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.
Abstract:
Although nutrient availability is a major driver of cell growth, and continuous adaptation to nutrient supply is critical for the development and survival of all organisms, the molecular mechanisms of nutrient sensing are only beginning to emerge. Here, we highlight recent advances in the field of nutrient sensing and discuss arising principles governing how metabolism might regulate growth-promoting pathways. In addition, we discuss signaling functions of metabolic enzymes not directly related to their metabolic activity.
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