Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Centrifugation

Centrifugation

Centrifugation is a separation technique based on differences in density or size. It is commonly used to separate solids from aqueous interferents. During centrifugation, the sample is placed in centrifugation tubes and spun at high angular velocity, which allows centrifugal force to act differentially on the different densities or masses of the components. After spinning, the supernatant liquid is decanted. Depending on the specific application, either the pellet or the supernatant is retained...

Mass Analyzers: Overview

Mass Analyzers: Overview

The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Analysis of factors affecting long-term survival in patients with anaplastic thyroid carcinoma and the efficacy of immunotherapy].

Zhonghua zhong liu za zhi [Chinese journal of oncology]·2025

Same author

In Situ Structural Characterization of Cardiomyocyte Microenvironment by Multimodal STED Microscopy.

Photonics·2024

Same author

Quantification of cardiac capillarization in basement-membrane-immunostained myocardial slices using Segment Anything Model.

Scientific reports·2024

Same author

[Application of machine learning in risk assessment for acute coronary syndrome].

Zhonghua xin xue guan bing za zhi·2024

Same author

Management of autofluorescence in formaldehyde-fixed myocardium: choosing the right treatment.

European journal of histochemistry : EJH·2023

Same author

Cooperation between myofibril growth and costamere maturation in human cardiomyocytes.

Frontiers in bioengineering and biotechnology·2022

Search research articles

Related Experiment Video

Updated: May 8, 2026

Spatial Separation of Molecular Conformers and Clusters

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

Large-angular separation of particles induced by cascaded deflection angles in optical sorting.

X-C Yuan¹, S W Zhu, J Bu

¹Institute of Modern Optics, Key Laboratory of Optoelectronic Information Science and Technology, Ministry of Education of China, Nankai University, Tianjin 300071, China.

Applied Physics Letters

|September 3, 2013

Summary

A novel composite microlens array (MLA) enables efficient, continuous microfluidic sorting by separating particles based on refractive index. This passive optical system achieves large lateral separation without complex assembly.

More Related Videos

Setting a Successful Sorting for Extracellular Vesicle Isolation

Setting a Successful Sorting for Extracellular Vesicle Isolation

Published on: October 11, 2024

Related Experiment Videos

Last Updated: May 8, 2026

Spatial Separation of Molecular Conformers and Clusters

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

Setting a Successful Sorting for Extracellular Vesicle Isolation

Setting a Successful Sorting for Extracellular Vesicle Isolation

Published on: October 11, 2024

Area of Science:

Optics and Photonics
Microfluidics
Biotechnology

Background:

Microfluidic systems are crucial for cell sorting and analysis.
Existing optical sorting methods often require complex setups and high power.
A need exists for passive, efficient microfluidic sorting techniques.

Purpose of the Study:

To develop a composite microlens array (MLA) for advanced microfluidic particle sorting.
To achieve large lateral separation of microparticles based on their properties.
To demonstrate a passive, high-power, and continuous optical sorting method.

Main Methods:

Fabrication of a composite microlens array with two cascaded guiding axes.
Projection of a composite focal spot pattern into a microchamber.
Utilizing optical forces for passive microfluidic sorting within a microscopic system.

Main Results:

Demonstrated passive, high-power, efficient, and continuous microfluidic sorting.
Achieved large lateral separation of particles with different refractive indices.
Experimentally verified separation to a lateral angle of 40° using moderate laser power.

Conclusions:

The developed MLA offers a simplified and effective approach for microfluidic sorting.
This technology enables precise separation of microparticles without complicated optical assembly.
The method holds potential for various applications in microscopic analysis and manipulation.