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Related Concept Videos

Typical Model Studies01:30

Typical Model Studies

Fluid mechanics model studies often utilize scaled-down systems to predict fluid behavior in full-scale environments, such as river flows, dam spillways, and structures interacting with open surfaces. Maintaining Froude number similarity in river models is crucial, as it replicates surface flow features like wave patterns and velocities.
Design Example: Creating a Hydraulic Model of a Dam Spillway01:21

Design Example: Creating a Hydraulic Model of a Dam Spillway

Scaled hydraulic models of dam spillways provide a practical way to replicate and study the intricate flow dynamics of these structures. Often built to a 1:15 ratio, these models allow for observing critical water behavior, such as velocity distribution, flow patterns, and energy dissipation.
Euler's Formula to Columns with Other End Conditions01:15

Euler's Formula to Columns with Other End Conditions

Euler's formula is very important in the field of structural engineering, providing a foundation for understanding the critical loading conditions of pin-ended columns. This formula links the modulus of elasticity, the moment of inertia of the cross-section, and the column's length, offering a precise calculation of the critical load at which a column is prone to buckling.
Fluid Pressure over Curved Plate of Constant Width01:12

Fluid Pressure over Curved Plate of Constant Width

When a curved plate of constant width is submerged in a liquid, the pressure acting normal to the plate varies continuously both in magnitude and direction. Calculating the magnitude and location of the resultant force at a point is often challenging for such cases. One of the methods to determine the resultant force and its location involves separately calculating the horizontal and vertical components of the resultant force. This complex calculation can be simplified by representing the...
Bending of Members Made of Several Materials01:11

Bending of Members Made of Several Materials

In analyzing a structural member composed of two different materials with identical cross-sectional areas, it is crucial to understand how their distinct elastic properties affect the member's response under load. The analysis involves assessing stress and strain distributions using the transformed section concept, which accounts for variations in material properties.
Hooke's Law determines stress in each material, stating that stress is proportional to strain but varies due to each material's...
Fluid Pressure over Flat Plate of Variable Width01:02

Fluid Pressure over Flat Plate of Variable Width

When a flat plate is submerged in a fluid, the fluid exerts pressure on the plate. This pressure can lead to many different phenomena, including drag and buoyancy. To understand the behavior of the fluid over a flat plate of variable width, it is essential to analyze the distribution of the pressure exerted.
The pressure distribution on the plate can be calculated by determining the force that acts on a differential area strip of the plate. Thus, the magnitude of the force is equal to the...

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Related Experiment Video

Updated: May 8, 2026

Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery
06:18

Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery

Published on: December 6, 2024

A comparative study on plaque vulnerability using constitutive equations.

A Karimi1, M Navidbakhsh, S Faghihi

  • 11Tissue Engineering and Biomaterials Division, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran.

Perfusion
|September 4, 2013
PubMed
Summary

Hypocellular atherosclerotic plaque exhibits the highest stress, indicating a high risk of rupture. Calcified plaque is more stable with lower stress values, aiding in vulnerability prediction.

Keywords:
atherosclerosisconstitutive equationscoronary arteryfinite element methodplaque vulnerability

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A Method to Study the Correlation Between Local Collagen Structure and Mechanical Properties of Atherosclerotic Plaque Fibrous Tissue
13:45

A Method to Study the Correlation Between Local Collagen Structure and Mechanical Properties of Atherosclerotic Plaque Fibrous Tissue

Published on: November 11, 2022

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Research
  • Materials Science

Background:

  • Atherosclerosis involves plaque buildup in arteries, a leading cause of heart attack and stroke.
  • Peak plaque stress is a critical factor in plaque rupture events.
  • Understanding plaque mechanics is crucial for predicting cardiovascular events.

Purpose of the Study:

  • To predict plaque vulnerability using finite element analysis (FEA) on human coronary artery samples.
  • To compare stress distributions in different plaque types (hypocellular, cellular, calcified).
  • To evaluate the performance of different hyperelastic models (Ogden, Mooney-Rivlin, Neo-Hookean) in predicting plaque stress.

Main Methods:

  • Human coronary arteries (14 healthy, 9 atherosclerotic) were tested postmortem.
  • Mechanical properties were obtained using uniaxial tensile testing.
  • Finite element models were developed using Ogden, Mooney-Rivlin, and Neo-Hookean hyperelastic models.
  • Peak plaque stresses were calculated and compared across different plaque compositions.

Main Results:

  • Hypocellular plaque consistently showed the highest stress values across all three models.
  • Calcified plaque exhibited the lowest stress values, indicating greater stability.
  • The Ogden model provided comparable stress predictions to Mooney-Rivlin and Neo-Hookean models.

Conclusions:

  • Hypocellular plaque composition is associated with the highest vulnerability to rupture.
  • Calcified plaque is mechanically more stable.
  • FEA-based plaque vulnerability prediction has significant clinical implications for interventions and surgical procedures.