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Related Concept Videos

Overview of Cell Signaling01:23

Overview of Cell Signaling

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate with the environment.
Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...
Overview of Cell Signaling01:23

Overview of Cell Signaling

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate with the environment.
Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...
What is Cell Signaling?02:03

What is Cell Signaling?

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.
What is Cell Signaling?02:03

What is Cell Signaling?

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.
Cell-surface Signaling01:21

Cell-surface Signaling

Hormones—or any molecule that binds to a receptor, known as a ligand—that are lipid-insoluble (water-soluble) are not able to diffuse across the cell membrane. In order to be able to affect a cell without entering it, these hormones bind to receptors on the cell membrane. When a first messenger, a hormone, binds to a receptor, a signal cascade is set off, causing second messengers, proteins inside the cell, to become activated, resulting in downstream effects.

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Related Experiment Video

Updated: May 8, 2026

Silicon Microchips for Manipulating Cell-cell Interaction
23:21

Silicon Microchips for Manipulating Cell-cell Interaction

Published on: August 30, 2007

Engineered cell-cell communication and its applications.

Stephen Payne1, Lingchong You

  • 1Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.

Advances in Biochemical Engineering/Biotechnology
|September 5, 2013
PubMed
Summary
This summary is machine-generated.

Scientists are engineering gene circuits for cell-cell communication to create complex biological functions. This synthetic biology approach offers insights into natural systems and enables novel applications.

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BioMEMS and Cellular Biology: Perspectives and Applications
16:30

BioMEMS and Cellular Biology: Perspectives and Applications

Published on: October 1, 2007

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Last Updated: May 8, 2026

Silicon Microchips for Manipulating Cell-cell Interaction
23:21

Silicon Microchips for Manipulating Cell-cell Interaction

Published on: August 30, 2007

BioMEMS and Cellular Biology: Perspectives and Applications
16:30

BioMEMS and Cellular Biology: Perspectives and Applications

Published on: October 1, 2007

Area of Science:

  • * Synthetic biology
  • * Cellular engineering
  • * Systems biology

Background:

  • * Intercellular communication is crucial in biological systems, from biofilms to neural networks.
  • * Understanding cell-cell signaling drives advancements in biological engineering.
  • * Natural communication systems provide blueprints for synthetic applications.

Purpose of the Study:

  • * To explore the engineering potential of intercellular communication.
  • * To develop synthetic gene circuits for programming cellular behavior.
  • * To investigate applications in synthetic biology and fundamental research.

Main Methods:

  • * Design and implementation of synthetic gene circuits.
  • * Programming spatiotemporal dynamics in cell populations.
  • * Utilizing principles of intercellular communication for engineering robust functions.

Main Results:

  • * Demonstrated the creation of diverse gene circuits using cell-cell communication.
  • * Successfully programmed spatiotemporal dynamics in engineered cell populations.
  • * Established a framework for engineering complex functions via synthetic biology.

Conclusions:

  • * Intercellular communication is a powerful tool for synthetic biology.
  • * Engineered gene circuits can mimic and extend natural biological functions.
  • * This approach offers new avenues for biological research and applications.