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Related Experiment Video

Updated: May 8, 2026

Immunofluorescence to Monitor the Cellular Uptake of Human Lactoferrin and its Associated Antiviral Activity Against the Hepatitis C Virus
06:28

Immunofluorescence to Monitor the Cellular Uptake of Human Lactoferrin and its Associated Antiviral Activity Against the Hepatitis C Virus

Published on: October 1, 2015

[Cycloferon in therapy of hyperplastic laryngitis for decrease of the number of relapses].

S S Grigorian, M G Romantsov, E V Demchenko

    Eksperimental'Naia I Klinicheskaia Farmakologiia
    |September 7, 2013
    PubMed
    Summary
    This summary is machine-generated.

    Chronic hyperplastic laryngitis can lead to cancer due to persistent inflammation and viral infections like Epstein-Barr virus (EBV). Interferon therapy with cycloferon improved recovery rates and reduced relapses in patients.

    Related Experiment Videos

    Last Updated: May 8, 2026

    Immunofluorescence to Monitor the Cellular Uptake of Human Lactoferrin and its Associated Antiviral Activity Against the Hepatitis C Virus
    06:28

    Immunofluorescence to Monitor the Cellular Uptake of Human Lactoferrin and its Associated Antiviral Activity Against the Hepatitis C Virus

    Published on: October 1, 2015

    Area of Science:

    • Otolaryngology
    • Oncology
    • Infectious Diseases

    Background:

    • Chronic hyperplastic laryngitis presents with persistent, recurrent inflammation, increasing the risk of laryngeal malignancy.
    • Laryngeal bacterization by Epstein-Barr virus (EBV) and Mycoplasma, coupled with interferon system imbalance, contributes to disease progression.

    Purpose of the Study:

    • To investigate the clinical characteristics of chronic hyperplastic laryngitis.
    • To evaluate the efficacy of interferon therapy, specifically cycloferon, in managing this condition.

    Main Methods:

    • Clinical observation of patients with chronic hyperplastic laryngitis.
    • Assessment of laryngeal bacterization by Epstein-Barr virus (EBV) and Mycoplasma.
    • Evaluation of interferon system status.
    • Treatment with cycloferon, an interferon inducer.

    Main Results:

    • Clinical recovery was observed in 57.4% of patients treated with cycloferon, varying by clinical form.
    • Interferon therapy with cycloferon demonstrated a reduction in the number of disease relapses.

    Conclusions:

    • Chronic hyperplastic laryngitis is associated with EBV and Mycoplasma infections and carries a risk of malignant transformation.
    • Cycloferon, as part of a comprehensive treatment plan, effectively improves clinical recovery and reduces recurrence in chronic hyperplastic laryngitis.