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Updated: May 8, 2026

Experimental Human Pneumococcal Carriage
Published on: February 15, 2013
[Pneumococcal lobar (croupose) pneumonias: clinical and morphological characteristics]
Abstract:
The paper presents data on morbidity and mortality rates from pneumococcal pneumonias and current views on the properties of pneumococcus. Analysis of the autopsy specimens obtained from Irkutsk and Saint-Petersburg shows that pneumococcal lobar pneumonia remains a common disease. A lethal outcome more frequently occurs during the first 24 hours of hospitalization, there is a high rate of discrepancy between the clinical and autopsy diagnoses. Cooling and alcoholic intoxication are the most important risk factors. Pneumococcus is virtually the only etiologic factor of lobar pneumonia, even in cases with negative postmortem bacteriology results. Among their complications, there are greatly important purulent meningitides and menigoencephalitides and leukopenia. By and large, V.D. Zinserling's views on the morphogenesis of croupose pneumonia are confirmed. It is shown that there may be three types of gray hepatization depending on neutrophil leukocyte/fibrin ratios. The incidence and clinical value of involvements of the myocardium, kidneys, and other organs have been determined.
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