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Updated: May 8, 2026
13:41
Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
Published on: March 8, 2012
[Transfer factor effectiveness patients with persistent genital human papillomavirus infection]
Blanca María Morfin-Maciel1, Julieta Margarita Sotelo-Ortiz
1Anexo Hospital Angeles Mocel, Ignacio Esteva 107 consultorio 206, MÈxico 11850 D.F. blancamorfin@hotmail.com.
Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|September 7, 2013
Summary
Transfer factor (TF) effectively resolved genital lesions in women with persistent human papillomavirus (HPV) infections. This immunomodulator treatment prevented recurrences for at least one year, offering a novel therapeutic approach.
Area of Science:
- Immunology
- Gynecology
- Infectious Diseases
Background:
- Human papillomavirus (HPV) is a common sexually transmitted infection, with persistent infections posing a high risk for cervical intraepithelial neoplasia.
- Transfer factor (TF) is an immunomodulator with a history of use in treating intracellular infections.
Purpose of the Study:
- To evaluate the efficacy of transfer factor (TF) as a treatment for persistent genital human papillomavirus (HPV) infections in women.
Main Methods:
- A group of 13 women with persistent HPV infections received daily transfer factor (TF) for five days, followed by weekly doses for five weeks.
- Patients had previously undergone various local and ablative therapies without success.
Main Results:
- Significant clinical improvement was observed in gynecological evaluations of cervical, vaginal, vulvar, and perineal lesions.
- No recurrences of HPV-related lesions were reported in any patient during at least one year of follow-up.
Conclusions:
- Transfer factor (TF) treatment led to the resolution of genital lesions in women with persistent HPV infections.
- The treatment demonstrated sustained efficacy, with no recurrences observed for at least one year post-therapy.
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