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Updated: May 8, 2026

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
Published on: March 1, 2024
Severe dental caries as the first presenting clinical feature in primary Sjögren's syndrome
Elham Ahmadi1, Sasan Fallahi, Mojgan Alaeddini
1Shahrekord University of Medical Sciences, Shahrekord, Iran. ; Dental Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Background:
Sjögren's syndrome is an autoimmune syndrome involving the exocrine glands specially the salivary and lacrimal glands leading to xerostomia and xerophtalmia. This paper presents a case with primary Sjögren's syndrome that severe dental caries were the first clinical manifestation.
Case Presentation:
A 42-year-old man was referred to the School of Dentistry, Tehran University of Medical Sciences due to unexplained severe dental decays. After systematic evaluation and consultation with the rheumatologist and the ophthalmologist, the diagnosis of primary Sjögren's syndrome was suggested and confirmed by serologic and histopathologic study.
Conclusion:
Primary Sjögren's syndrome should be considered in the differential diagnosis of patients with early severe dental caries.
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