Related Experiment Video
Updated: May 8, 2026

Measurements of Physiological Stress Responses in C. Elegans
Published on: May 21, 2020
APETALA2/Ethylene Responsive Factor (AP2/ERF) transcription factors: mediators of stress responses and developmental
Francesco Licausi1, Masaru Ohme-Takagi, Pierdomenico Perata
1Institute of Life Sciences, Scuola Superiore Sant’Anna, Pisa, Italy.
Abstract:
Transcription factors belonging to the APETALA2/Ethylene Responsive Factor (AP2/ERF) family are conservatively widespread in the plant kingdom. These regulatory proteins are involved in the control of primary and secondary metabolism, growth and developmental programs, as well as responses to environmental stimuli. Due to their plasticity and to the specificity of individual members of this family, AP2/ERF transcription factors represent valuable targets for genetic engineering and breeding of crops. In this review, we integrate the evidence collected from functional and structural studies to describe their different mechanisms of action and the regulatory pathways that affect their activity.
Related Concept Videos
Master Transcription Regulators
Cell Signaling in Plants
Regulation of the Unfolded Protein Response
RNA Polymerase II Accessory Proteins
The Unfolded Protein Response
Other Stress Responses in Bacteria

