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Acquired perforating dermatosis: a clinical and dermatoscopic correlation
Marigdalia K Ramirez-Fort1, Farhan Khan, Cliff O Rosendahl
1Center for Clinical Studies, 1401 Binz St., Houston, TX 77004, USA.
Dermatology Online Journal
|September 10, 2013
Summary
Acquired Perforating Dermatosis (APD) is a skin condition where dermal material is eliminated through the epidermis. It frequently occurs in patients with chronic renal failure (CRF) or diabetes mellitus (DM).
Area of Science:
- Dermatology
- Nephrology
- Endocrinology
Background:
- Acquired Perforating Dermatosis (APD) is a rare skin disorder characterized by transepidermal elimination of dermal components.
- APD typically manifests in adulthood and is associated with several systemic conditions.
Observation:
- The abstract highlights a strong association between APD and chronic renal failure (CRF), particularly in patients undergoing dialysis.
- Diabetes mellitus (DM) is also frequently linked to the development of APD.
Findings:
- Studies indicate that up to 10% of patients on hemodialysis may develop APD.
- A significant majority of APD cases (16 out of 22) were found to be associated with CRF in one study.
Implications:
- These findings underscore the importance of recognizing APD in patients with CRF and DM.
- Increased awareness and screening for APD in at-risk populations may improve patient outcomes and management.
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