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Updated: Jul 8, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Endovascular Therapy for Acute Ischemic Stroke: Current Evidence and Evolving Practices
Brandon Doan1,2, Mohamad Abdalkader1, Farhan Khan3
1Departments of Radiology, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.
Purpose Of Review:
This literature review highlights the recent evidence and guidelines for endovascular therapy (EVT) in patients with large-core infarctions, basilar artery occlusions, and patients presenting in the late-window.
Recent Findings:
EVT provides a functional benefit for patients with large-core infarcts compared to medical management. Similar improvements have been observed in basilar artery occlusions. EVT has also demonstrated reduced disability in late-window presentations when selected by computed tomography angiogram/perfusion (CTA/CTP), or magnetic resonance imaging (MRI). New evidence suggests noncontrast CT (NCCT)-based selection may be an effective alternative. EVT can reduce disability in patients with small and large-core infarcts, basilar artery occlusions, and late-window presentations compared to medical management. To broaden patient eligibility, future research is needed to clarify EVT's efficacy in very large-core infarcts, mild severity strokes, and patients with medium vessel occlusion.
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