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Facial calcinosis: case report
Lorna Craggs1, Ahmet Ferhat Misir, Mehmet Manisali
1Croydon University Hospital, United Kingdom.
The British Journal of Oral & Maxillofacial Surgery
|September 10, 2013
Summary
Antisynthetase syndrome, a rare inflammatory muscle disease, can manifest with unusual symptoms. This case highlights subcutaneous calcinosis in the submandibular region of a patient with known antisynthetase syndrome.
Area of Science:
- Rheumatology
- Immunology
- Dermatology
Background:
- Antisynthetase syndrome is a rare autoimmune disorder.
- It is characterized by myositis, interstitial lung disease, arthritis, and Raynaud phenomenon.
Observation:
- A 34-year-old woman with a known diagnosis of antisynthetase syndrome presented with a specific clinical finding.
- The patient exhibited subcutaneous calcinosis, which is the deposition of calcium in soft tissues.
Findings:
- The calcinosis was located bilaterally in the submandibular region, a less common presentation.
- This case expands the known spectrum of cutaneous manifestations in antisynthetase syndrome.
Implications:
- Subcutaneous calcinosis may be an underrecognized feature of antisynthetase syndrome.
- Further research is needed to understand the pathogenesis and clinical significance of calcinosis in this condition.
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