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Updated: May 8, 2026

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect
05:04

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect

Published on: September 22, 2023

Breastfeeding promotion for management of neonatal abstinence syndrome

Ursula A Pritham

    Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN
    |September 12, 2013
    PubMed

    Insights

    Breastfeeding can reduce neonatal abstinence syndrome (NAS) severity in infants exposed to methadone or buprenorphine during pregnancy. This practice, alongside skin-to-skin contact, aids in managing NAS symptoms and improving infant outcomes.

    Area of Science:

    • Neonatal care
    • Pharmacology
    • Public Health

    Background:

    • Neonatal Abstinence Syndrome (NAS) is a concern for infants exposed to opioids in utero.
    • Opioid replacement therapies like methadone and buprenorphine are commonly used during pregnancy.
    • The impact of breastfeeding on NAS severity and management requires further understanding.

    Purpose of the Study:

    • To review literature on the association between breastfeeding and NAS severity.
    • To examine the role of breastfeeding in the need for pharmacologic treatment for NAS.
    • To assess the effect of breastfeeding on hospital length of stay for neonates exposed to methadone or buprenorphine.

    Main Methods:

    • Literature search of PubMed, CINAHL, and Medline (1990-2013).
    • Keywords included opioid dependency, NAS, methadone, buprenorphine, breastfeeding, and related terms.
    • Inclusion criteria focused on English-language studies concerning breastfeeding for NAS management.

    Main Results:

    • Breastfeeding effectively decreases NAS symptoms due to methadone and buprenorphine transfer via breast milk.
    • Maternal contact during breastfeeding plays a significant role in ameliorating NAS symptoms.
    • Supportive interventions like skin-to-skin contact, swaddling, and rooming-in enhance breastfeeding benefits for NAS.

    Conclusions:

    • Clinicians should understand the benefits of breastfeeding for opioid-dependent mothers and neonates.
    • Breastfeeding can be safely recommended to improve the long-term health of high-risk infants.
    • This review assists clinicians in supporting opioid-dependent women to successfully breastfeed their infants.
    Abstract

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