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Relationship between coronary artery stenosis and cardio-ankle vascular index (CAVI) in patients undergoing

Masafumi Kanamoto1, Naoki Matsumoto, Tatsuya Shiga

  • 1Gunma University Hospital Intensive Care Unit, Japan.

Journal of Cardiovascular Disease Research
|September 12, 2013
PubMed

Insights

The cardio-ankle vascular index (CAVI) is a reliable measure of arterial stiffness, unaffected by anesthesia-induced blood pressure changes. Higher CAVI values indicate a greater likelihood of coronary artery disease (CAD).

Area of Science:

  • Cardiovascular Medicine
  • Vascular Biology
  • Medical Diagnostics

Background:

  • The cardio-ankle vascular index (CAVI) assesses arterial stiffness, independent of blood pressure fluctuations.
  • Coronary artery disease (CAD) is a significant health concern, and early detection is crucial.
  • Understanding the impact of anesthesia on vascular markers is important for surgical patients.

Purpose of the Study:

  • To investigate the relationship between CAVI and coronary artery disease (CAD).
  • To evaluate the effect of rapid blood pressure changes during anesthesia induction on CAVI.
  • To determine if CAVI can predict atherosclerosis and coronary artery stenosis.

Main Methods:

  • CAVI was measured in 76 patients before and after anesthesia for cardiovascular surgery.
  • Patients were grouped based on the presence (CAD) or absence (0VD) of coronary artery disease.
  • CAD patients were further classified by the number of stenotic vessels (1VD, 2VD, 3VD).

Main Results:

  • Systolic blood pressure decreased significantly post-anesthesia, but CAVI remained unchanged.
  • No correlation was found between blood pressure changes and pre-anesthetic CAVI.
  • CAVI values were significantly higher in patients with CAD compared to those without (P < 0.05).

Conclusions:

  • CAVI is a reproducible measure of arterial stiffness, unaffected by anesthesia and blood pressure variations.
  • Elevated CAVI is significantly associated with the presence of coronary artery disease.
  • CAVI shows potential as a predictive tool for atherosclerosis and coronary artery stenosis in surgical patients.
Abstract

Keywords:
AnesthesiaAtherosclerosisCardio-ankle vascular indexCardiovascular surgery

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