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Transdermal delivery: product and patent update
1Department of Pharmacal Sciences, Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USA. Dr.hgupta@yahoo.com.
Transdermal drug delivery offers a viable alternative for medications, especially those affected by first-pass metabolism. This review details 16 drugs and 22 products, alongside clinical trials and recent patents in transdermal systems.
Area of Science:
- Pharmacology
- Drug Delivery Systems
- Biotechnology
Background:
- Transdermal drug delivery bypasses oral and parenteral routes, ideal for drugs undergoing first-pass metabolism.
- It enables controlled dosing and sustained therapeutic blood levels.
- This method presents an attractive alternative for various pharmaceutical applications.
Purpose of the Study:
- To provide an updated review of transdermal drug delivery systems.
- To compile information on marketed transdermal products, clinical trials, and recent patents.
- To serve as a comprehensive resource for transdermal drug delivery research.
Main Methods:
- Literature review of transdermal drug delivery systems.
- Compilation of 16 drugs and 22 marketed products.
- Summary of recent patents (last 5 years) and ongoing clinical trials.
Main Results:
- Detailed information on 16 specific drugs and 22 transdermal products is presented.
- An overview of current clinical trials in transdermal systems is provided.
- Key patents granted in the last five years across various pharmacological categories are summarized.
Conclusions:
- Transdermal drug delivery is a significant area of pharmaceutical research and development.
- The review consolidates essential information on products, trials, and patents, aiding researchers.
- This work highlights the growing importance and innovation in transdermal therapeutics.
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