Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sarcopenia as a Predictor of Mortality Following Vertebral Compression Fractures Treated With Vertebroplasty.

Global spine journal·2026
Same author

Response to the letter to the editor: Predicting residual neurologic deficits using the Spinal Infection Treatment Evaluation score after surgery for thoracic and lumbar spinal epidural abscess: a retrospective study in Taiwan.

Asian spine journal·2026
Same author

Lumbar Spine Endplate Sclerosis is a Protective Factor for Cage Subsidence in Minimally Invasive Transforaminal Lumbar Interbody Fusion.

Global spine journal·2025
Same author

Safety and functional evaluation of a synthetic lamina cover that replaces lost autologous spinal bone after laminectomy, in a sheep and human study.

North American Spine Society journal·2025
Same author

CT-based hounsfield unit as an alternative osteoporosis assessment in ankylosing spondylitis patients with bamboo spine.

Scientific reports·2025
Same author

Predicting residual neurologic deficits using the Spinal Infection Treatment Evaluation score after surgery for thoracic and lumbar spinal epidural abscess: a retrospective study in Taiwan.

Asian spine journal·2025
Same journal

Recurrence after modified Type III cordectomy for glottic cancer: Predisposing factors and management.

Journal of the Chinese Medical Association : JCMA·2026
Same journal

Incidence of Jarisch-Herxheimer Reaction After Syphilis Treatment and the Role of Awareness Effect.

Journal of the Chinese Medical Association : JCMA·2026
Same journal

Respiratory syncytial virus infection in adults: Clinical manifestations, outcomes, and vaccines.

Journal of the Chinese Medical Association : JCMA·2026
Same journal

Causal effects among hypertension, osteoporosis, and metabolites: A Mendelian randomization study.

Journal of the Chinese Medical Association : JCMA·2026
Same journal

Clinical utility of preoperative lymphocyte-albumin-neutrophil ratio for prognostication in oral cancer patients undergoing surgery.

Journal of the Chinese Medical Association : JCMA·2026
Same journal

Effects of insulin and exenatide therapy on glycemic control and β-cell function in patients newly diagnosed with type 2 diabetes and severe hyperglycemia.

Journal of the Chinese Medical Association : JCMA·2026
See all related articles

Related Experiment Videos

Primary cervical osteomyelitis.

Chuan-En Tsai1, Fang-Tsai Lee, Ming-Chau Chang

  • 1Department of Orthopedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.

Journal of the Chinese Medical Association : JCMA
|September 13, 2013
PubMed
Summary
This summary is machine-generated.

Cervical osteomyelitis from Staphylococcus aureus presents acutely with high CRP, while Propionibacterium acnes and tuberculosis infections are indolent, causing more bone destruction. Surgical fusion is effective for cervical osteomyelitis.

Keywords:
Propionibacterium acnesStaphylococcus aureuscervical osteomyelitissurgerytuberculosis

Related Experiment Videos

Area of Science:

  • Orthopedics
  • Infectious Diseases
  • Neurosurgery

Background:

  • Cervical osteomyelitis is rare, often diagnosed late, with poorly understood pathogen characteristics and treatment guidelines.
  • This study focuses on primary cervical osteomyelitis, a challenging condition due to its location and potential for delayed diagnosis.

Purpose of the Study:

  • To differentiate cervical osteomyelitis based on causative pathogens (Staphylococcus aureus, Propionibacterium acnes, Mycobacterium tuberculosis).
  • To evaluate the clinical presentation, treatment outcomes, and surgical management of primary cervical osteomyelitis.

Main Methods:

  • Retrospective review of six primary cervical osteomyelitis cases treated between 2002-2012.
  • Analysis of patient data including symptoms, neurological function, C-reactive protein (CRP) levels, and imaging (plain film, MRI).
  • Surgical intervention involved anterior decompression, instrumentation, and autograft fusion.

Main Results:

  • Staphylococcus aureus (3 cases) showed acute onset, higher CRP (mean 173 mg/L), shorter diagnosis duration (7.2 weeks), and less bony destruction.
  • Propionibacterium acnes (2 cases) and Mycobacterium tuberculosis (1 case) presented indolently with lower CRP (mean 5.5 mg/L) and more severe bone destruction.
  • All patients achieved stable cervical alignment and fusion post-surgery, with improved neurological function and pain.

Conclusions:

  • Staphylococcus aureus cervical osteomyelitis is acute with high CRP and less bone damage, unlike indolent P. acnes and M. tuberculosis infections.
  • Anterior decompression, instrumentation, and autograft fusion are effective treatments for primary cervical osteomyelitis.
  • Mesh cages offer a viable alternative to autografts in surgical reconstruction.