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Published on: May 3, 2018
[Validity of cardiovascular prescriptions to the guidelines in the elderly according to the STOPP and START method]
Marie Coupet1, Delphine Renvoize, Camille Rousseau
1Service de médecine gériatrique, Hôpital Decker, Centre hospitalier Bretagne Atlantique, Vannes, France.
Insights
Medical prescriptions for elderly patients with cardiovascular diseases often don't align with guidelines. Key issues include under-prescribing ACE inhibitors for heart failure and atrial fibrillation anticoagulation, highlighting areas for improved geriatric care.
Area of Science:
- Geriatric Medicine
- Cardiology
- Pharmacology
Context:
- Cardiovascular diseases are a leading cause of mortality in the elderly.
- Assessing prescription appropriateness against clinical guidelines is crucial for this demographic.
- Geriatric units hospitalize a significant number of elderly patients with complex health needs.
Purpose:
- To evaluate the adherence of cardiovascular medication prescriptions to established guidelines in elderly patients.
- To identify specific areas of non-compliance, including inappropriate prescriptions and under-prescribing.
Summary:
- A retrospective analysis of 736 geriatric patients (mean age 86.7) revealed prescription discrepancies.
- Inappropriate prescriptions included calcium channel blockers with constipation (9%) and high-dose aspirin (>150mg/day) (8.4%).
- Under-prescribing was noted for ACE inhibitors in heart failure (19%) and post-myocardial infarction (15.8%), and anticoagulation for atrial fibrillation (11%).
Impact:
- Identified significant gaps between clinical practice and guidelines for heart failure and atrial fibrillation management in the elderly.
- Highlights the need for improved prescribing, particularly considering factors like advanced age, dependency, and renal insufficiency.
- Suggests opportunities for optimizing cardiovascular care in geriatric populations to reduce mortality and morbidity.
Abstract:
Cardiovascular diseases are the first cause of death in elderly patients. So it seems important to estimate the adequacy of the medical prescriptions to the guidelines in this population and for these diseases. A retrospective analysis was performed in nine hospitals on 736 patients aged 65 years old and over hospitalized in the acute care geriatric unit. Cardiovascular prescribing were analyzed for each patient according to STOPP and START. The population (n=736) has a mean age of 86.7 years and belongs in 45.0% of the cases to the group of dependence GIR3-4. According to STOPP, two inappropriate prescriptions are noticed: calcium channel blockers with chronic constipation concerning 9% of the included population and aspirin at dose > 150 mg/day representing 8.4% of this population. According to START, angiotensin converting enzyme inhibitor are under-prescribed in elderly patients with heart failure (140 patients = 19.0% of the population) and following acute myocardial infarction (116 patients = 15.8%). Anticoagulation in patients with atrial fibrillation is also under-prescribed: 82 patients are concerned (11.0% of the population). The prescription of ACE inhibitor is influenced by renal insufficency in patients with heart failure. The anticoagulation in atrial fibrillation is age and dependence-related. This analysis demonstrates an inadequacy between the clinical practice and guidelines for two major cardiovascular diseases: the heart failure and the atrial fibrillation. The importance of the inadequacy was suspected of opportunities for improvement, in particular in the presence of their risk factors: very elderly patients, loss of autonomy and renal insufficiency.
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