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The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...

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Related Experiment Video

Updated: May 7, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
06:38

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

Published on: April 12, 2017

Primary renal carcinoid tumor.

K V Kanodia1, A V Vanikar, R D Patel

  • 1Department of Pathology, Dr. H. L. Trivedi Institute of Transplantation Sciences, Gujarat, India. kamalkanodia@yahoo.com

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
|September 14, 2013
PubMed
Summary
This summary is machine-generated.

Primary renal carcinoid tumors are exceptionally rare, with limited understanding of their development and outcomes. This report details a case of primary renal carcinoid in a young man successfully treated with radical nephrectomy.

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Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
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Last Updated: May 7, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
06:38

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

Published on: April 12, 2017

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
11:27

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy

Published on: April 29, 2014

Area of Science:

  • Oncology
  • Urology

Background:

  • Primary renal carcinoid tumors are exceedingly rare neuroendocrine neoplasms originating in the kidney.
  • Their pathogenesis, clinical presentation, and prognostic factors remain poorly understood due to limited case reports.

Observation:

  • A case of primary renal carcinoid tumor is presented in a 26-year-old male patient.
  • The tumor was identified as originating from the kidney, distinct from metastatic carcinoid disease.

Findings:

  • The patient underwent radical nephrectomy for the primary renal carcinoid tumor.
  • Surgical management via radical nephrectomy was employed for this rare renal neoplasm.

Implications:

  • This case contributes to the limited body of knowledge on primary renal carcinoid tumors.
  • Further research into the pathogenesis and long-term prognosis of these rare tumors is warranted.
  • Highlighting successful surgical intervention for primary renal carcinoid tumors.