Related Experiment Video
Updated: May 7, 2026

A Reproducible Cartilage Impact Model to Generate Post-Traumatic Osteoarthritis in the Rabbit
Published on: November 21, 2023
Mechanical causes of osteoarthritis in young adults
Abstract:
Femoroacetabular impingement is a very common cause of secondary osteoarthritis (OA) in the young adult. It is an important co-factor in the better recognized prearthritic deformities such as residual hip dysplasia (RHD), Perthes disease and slipped capital femoral epiphysis (SCFE). Another subgroup of patients has isolated malrotation of the hip joint and/or reduced femoral head-neck offset causing femoroacetabular impingement and chronic hip joint pain. Special clinical tests and imaging modalities can identify these patients at an early stage when they have little or no OA. The common biomechanical pathway for deformities causing chronic femoroacetabular impingement is local damage of the capsular-labrum complex and the cartilage. Understanding the anatomy, biomechanics and pathophysiology of these conditions of the hip joint is a prerequisite for planning treatment.
More Related Videos
06:27Non-Invasive Compression-Induced Anterior Cruciate Ligament (ACL) Injury and In Vivo Imaging of Protease Activity in Mice
Published on: September 29, 2023
08:42Real-time Visualization and Analysis of Chondrocyte Injury Due to Mechanical Loading in Fully Intact Murine Cartilage Explants
Published on: January 7, 2019
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
The Effect of Aging on Tissues
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Degenerative Disc Disease I: Introduction
Development of the Limb Synovial Joints
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...