Related Experiment Video
Updated: May 7, 2026

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay
Published on: April 28, 2022
Burn scar lipofilling: immunohistochemical and clinical outcomes
Agostino Bruno1, Giancarlo Delli Santi, Lucio Fasciani
1From the Burn Center and Plastic Surgery, S. Eugenio Hospital, Rome, Italy.
Abstract:
Over the past years, lipofilling has been used for many pathologies and sequelae; recently, its use has also widened for burn outcomes. A total of 93 burn scars were assessed (from September 2011 to February 2012). Half of scar area was treated through injection of adipose tissue harvested from subcutaneous fat and processed in accordance with the Coleman technique. Biopsy specimens were taken before treatment and at 3 and 6 months after the treatment. Histologic and immunohistochemical evaluations were conducted. In the samples examined, a marked improvement was observed, which can be seen in 3 months, but most of all, documented at 6 months. In addition, from a clinical point of view, an improvement has been documented, both functional and aesthetic. Lipofilling for burn scar complete and improve the results of standard surgical procedures, with long-term care setting and long-acting results.
