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Computing Confidence Bounds for Power and Sample Size of the General Linear Univariate Model
Douglas J Taylor1, Keith E Muller
1Douglas J. Taylor is a doctoral student, and Keith E. Muller is Associate Professor, Department of Biostatistics, University of North Carolina, Chapel Hill, NC 27599.
Abstract:
The power of a test, the probability of rejecting the null hypothesis in favor of an alternative, may be computed using estimates of one or more distributional parameters. Statisticians frequently fix mean values and calculate power or sample size using a variance estimate from an existing study. Hence computed power becomes a random variable for a fixed sample size. Likewise, the sample size necessary to achieve a fixed power varies randomly. Standard statistical practice requires reporting uncertainty associated with such point estimates. Previous authors studied an asymptotically unbiased method of obtaining confidence intervals for noncentrality and power of the general linear univariate model in this setting. We provide exact confidence intervals for noncentrality, power, and sample size. Such confidence intervals, particularly one-sided intervals, help in planning a future study and in evaluating existing studies.
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