Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bonanno's Theory of Grieving01:17

Bonanno's Theory of Grieving

Grieving is a complex psychological and emotional process that varies significantly among individuals. George Bonanno's research on bereavement identified four distinct patterns of grieving, offering a nuanced understanding of how people cope with significant loss, such as the death of a spouse, over extended periods. These patterns — resilience, recovery, chronic dysfunction, and delayed grief — highlight the diversity in emotional responses and adaptive mechanisms.
Resilience
The resilience...
Major Losses in Pipes01:28

Major Losses in Pipes

When a fluid flows through a pipe, it experiences energy losses due to frictional resistance along the pipe walls, known as major losses. These energy losses result in a pressure drop, which varies based on the flow conditions — whether laminar or turbulent — and the specific physical properties of the fluid and pipe.
Fluid flow can be classified as laminar or turbulent, primarily based on the Reynolds number. This dimensionless number reflects the relative influence of inertial to viscous...
Avoidance Learning and Learned Helplessness01:14

Avoidance Learning and Learned Helplessness

Avoidance learning and learned helplessness are critical concepts in understanding behavioral responses to negative stimuli.
Avoidance learning occurs when an organism learns that a specific behavior can prevent an unpleasant outcome. For example, a student who receives a bad grade may start studying harder to avoid future poor grades. This behavior persists even when the negative outcome is no longer present. Avoidance learning is powerful because it maintains behavior in the absence of the...
Ending Relationships01:28

Ending Relationships

The dissolution of intimate relationships presents complex emotional and psychological challenges, particularly when emotional bonds are strong, the relationship is long-standing, and perceived alternatives are limited. This distress often intensifies in romantic breakups, where the initiator may experience greater turmoil than the rejected partner. Contributing factors include residual attachment, guilt over causing pain, and uncertainty about how to manage the situation. The stress is further...
Minor Losses in Pipes01:25

Minor Losses in Pipes

In pipe systems, minor losses refer to energy losses arising from components such as valves, bends, fittings, expansions, and other features that disrupt the steady flow of fluid. These disturbances cause energy dissipation through turbulence and resistance, which engineers quantify to manage system efficiency effectively.
Valves play a significant role in generating minor losses by obstructing or redirecting the fluid flow. When a valve is closed or partially closed, it restricts the flow...
Coping Strategies: Emotion Focused01:20

Coping Strategies: Emotion Focused

Emotion-focused coping refers to a set of strategies aimed at managing the emotional impact of stressors, rather than directly addressing their causes. This approach involves altering one's emotional response to stressful situations to reduce their psychological effects. For example, individuals might talk with a friend or engage in activities like journaling to express their feelings. Such actions can help achieve emotional clarity or release, providing the psychological stability needed to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ruptoblasts: Explosive cytotoxicity from an ancient lineage.

Trends in cell biology·2026
Same author

Protocol for purifying and sequencing cell subpopulations based on RNA FISH signal in planaria.

STAR protocols·2026
Same author

Syrah: a pipeline to maximize spatial transcriptomics data output.

G3 (Bethesda, Md.)·2026
Same author

Extracellular vesicles mediate stem cell signaling and systemic RNAi in planarians.

Science advances·2026
Same author

Molecular and cellular characterization of planarian stem cell microenvironments.

Cell reports·2025
Same author

Metabolites produced by agat+ cells support regeneration in the planarian Schmidtea mediterranea.

Developmental biology·2025

Related Experiment Video

Updated: May 7, 2026

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum
04:36

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum

Published on: August 5, 2020

Learning about loss.

Alejandro Sánchez Alvarado1

  • 1is an eLife reviewing editor, and is at the Howard Hughes Medical Institute, Stowers Institute for Medical Research , Kansas City, Missouri , United States asa@stowers.org.

Elife
|September 17, 2013
PubMed
Summary

Researchers discovered that follistatin and activin genes are crucial for flatworms to detect wounds needing new tissue. This finding advances our understanding of tissue regeneration mechanisms in these organisms.

Area of Science:

  • Molecular Biology
  • Developmental Biology
  • Regenerative Medicine

Background:

  • Flatworms possess remarkable regenerative capabilities.
  • Understanding the genetic basis of wound identification is key to unlocking regenerative potential.

Purpose of the Study:

  • To identify genes involved in wound detection and subsequent tissue repair in flatworms.
  • To elucidate the molecular mechanisms underlying the regenerative response.

Main Methods:

  • Gene expression analysis in response to injury.
  • Functional studies of identified genes (follistatin and activin) in flatworm regeneration.

Main Results:

  • Follistatin and activin genes were identified as critical players in the wound identification process.

More Related Videos

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

Related Experiment Videos

Last Updated: May 7, 2026

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum
04:36

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum

Published on: August 5, 2020

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

  • These genes appear to regulate the initial steps of tissue regeneration.

    • Conclusions:

    • Follistatin and activin play a significant role in initiating the regenerative response in flatworms.
    • This research provides insights into conserved genetic pathways for tissue repair.