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Metabolism studies of ifenprodil, a potent GluN2B receptor antagonist

Evamaria Falck1, Frank Begrow, Eugen Verspohl

  • 1Institut für Pharmazeutische und Medizinische Chemie, Westfälische Wilhelms-Universität, Münster, Germany.

Journal of Pharmaceutical and Biomedical Analysis
|September 18, 2013
PubMed

Keywords:
BSACNSCOMTEICGluN2B receptor antagonistsIfenprodilIn vitro and in vivo metabolismLC–MSN-methyl-d-aspartateNADPHNMDANMDA receptorPAPSS-(5′-adenosyl)-l-methionine iodideSAMTICUDPGAadenosine-3′-phosphate-5′-phosphosulfate lithium salt hydratebovine serum albumincatechol-O-methyl transferasecentral nervous systemextracted ion currentnicotinamide adenine dinucleotide phosphatetotal ion currenturidine 5′-diphosphoglucuronic acid trisodium salt

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