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Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder
Published on: November 25, 2025
Outcomes of specialized residential treatment for adults with obsessive-compulsive disorder
Thröstur Björgvinsson1, Abpp John Hart, Chad Wetterneck
1At the time of the study: BJÖRGVINSSON, POWELL, and HEFFELFINGER: The Menninger Clinic and Baylor College of Medicine, Houston, TX; HART and BARRERA: The Menninger Clinic; WETTERNECK: University of Houston-Clear Lake; CHASSON: Towson University, Towson, MD; STANLEY: Baylor College of Medicine and Michael E. DeBakey VA Medical Center, Houston. Currently: BJÖRGVINSSON: the Houston OCD Program and McLean Hospital/Harvard Medical School; BARRERA: University of Houston; POWELL: Michael E. DeBakey Veterans Affairs Medical Center; HEFFELFINGER: the Houston OCD Program.
Abstract:
Cognitive-behavioral therapy (CBT) utilizing exposure and response prevention for obsessive- compulsive disorder (OCD) has typically been studied in the context of time-limited treatment conducted in outpatient settings. However, in practice, patients vary in their response to such treatment, and some require more prolonged participation to obtain optimal benefit. An intensive residential program is one alternative for patients who do not improve in traditional outpatient treatment. This naturalistic study evaluated 46 patients with a primary diagnosis of OCD who received intensive residential treatment between 2004 and 2008. Patients entering the program completed assessments at admission and at discharge. Results indicated statistically significant improvements on all outcome measures, with 60.9% of patients meeting criteria for clinically reliable change in OCD severity and 37% achieving high end-state functioning. Specialized residential treatment seems effective for treatment-refractory OCD, although future controlled trials with larger samples are needed.
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