Related Experiment Video
Updated: May 7, 2026
07:48
An Orthotopic Bladder Cancer Model for Gene Delivery Studies
Published on: December 1, 2013
Urinary bladder cancer in yemen.
Abdullah Saleh Al-Samawi1, Saleh Mansoor Aulaqi
1Department of Pathology, Faculty of Medicine and Health Sciences Sana'a University. PO Box 13078 Sana'a, Yemen.
Oman Medical Journal
|September 18, 2013
Summary
This study analyzed 316 bladder cancer cases in Yemen, finding urothelial neoplasms to be most common. The research highlights clinicopathological features and histological grading of these urinary bladder cancers.
Area of Science:
- Uropathology
- Oncology
- Public Health
Background:
- Urinary bladder cancer presents diverse clinicopathological features globally.
- Accurate histological grading is crucial for effective patient management and treatment strategies.
- Understanding regional variations in bladder cancer subtypes is essential for targeted public health initiatives.
Purpose of the Study:
- To characterize the clinicopathological features of urinary bladder cancer in Yemen.
- To histologically grade urothelial neoplasms using the WHO/ISUP 1998 classification.
- To provide data on bladder cancer epidemiology in the Yemeni population.
Main Methods:
- A descriptive, record-based study of 316 bladder cancer cases diagnosed between January 2005 and April 2009.
- Pathological diagnoses were confirmed by two pathologists using hematoxylin and eosin stained sections.
- Cases were classified according to the World Health Organization/International Society of Urologic Pathology (WHO/ISUP) 1998 criteria.
Main Results:
- Urothelial neoplasms constituted the majority (78%) of the 316 bladder cancer cases.
- Squamous cell carcinoma (17%) and adenocarcinoma (2%) were the next most frequent types.
- The study observed a male preponderance (4:1 ratio) with a peak incidence in the 61-70 age group.
Conclusions:
- Urothelial neoplasms are the predominant type of urinary bladder cancer in Yemen.
- Low-grade papillary urothelial carcinoma and high-grade non-papillary urothelial carcinoma were the most common subtypes.
- The findings underscore the importance of detailed histological classification for understanding bladder cancer in this region.
Related Concept Videos
01:23Urinary Bladder
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
01:20Disorders of the Male Reproductive System
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
01:26Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
01:21Nursing Assessment of the Genitourinary System I: Health History
The genitourinary system is critical to maintaining fluid balance, waste elimination, and reproductive function. Nurses play a vital role in assessing this system, beginning with a thorough health history. This process involves gathering patient information, identifying risk factors, and recognizing symptoms of genitourinary disorders. Early detection is vital for timely interventions and management.1. Gathering Patient InformationA complete health history includes the patient’s personal,...
01:30Urinary Tract Calculi III: Medical Management
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...